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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EOMES
All Species:
28.79
Human Site:
S646
Identified Species:
52.78
UniProt:
O95936
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O95936
NP_005433.2
686
72732
S646
A
C
K
R
R
R
L
S
P
S
N
S
S
N
E
Chimpanzee
Pan troglodytes
XP_001165803
690
73333
S650
A
C
K
R
R
R
L
S
P
S
N
S
S
N
E
Rhesus Macaque
Macaca mulatta
XP_001093085
737
80029
S697
A
C
K
R
R
R
L
S
P
S
N
S
S
N
E
Dog
Lupus familis
XP_850738
688
72729
S648
A
C
K
R
R
R
L
S
P
S
T
S
S
N
E
Cat
Felis silvestris
Mouse
Mus musculus
O54839
707
74783
S667
A
C
K
R
K
R
L
S
P
S
T
P
S
N
G
Rat
Rattus norvegicus
XP_001061749
663
70857
S623
A
C
K
R
K
R
L
S
P
T
T
S
S
N
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514679
386
42515
G347
S
G
L
Y
E
Q
D
G
K
R
R
R
L
S
P
Chicken
Gallus gallus
XP_426003
399
44936
S360
A
C
K
R
R
R
L
S
P
S
T
S
S
N
E
Frog
Xenopus laevis
P79944
692
75925
L653
G
A
C
K
R
R
R
L
S
P
S
T
S
S
N
Zebra Danio
Brachydanio rerio
NP_571754
661
71990
S622
A
C
K
R
R
R
V
S
P
G
G
S
S
T
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q24432
972
102538
F790
Q
G
L
K
S
H
R
F
S
P
Y
S
L
P
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q19691
423
46979
C382
L
A
K
A
S
S
E
C
K
V
E
A
T
S
E
Sea Urchin
Strong. purpuratus
XP_791266
946
105128
H757
N
A
D
S
K
T
I
H
Y
R
S
S
A
G
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
80
96.5
N.A.
87.5
81.6
N.A.
25.6
52.4
62.1
57.5
N.A.
22.9
N.A.
24.7
23.6
Protein Similarity:
100
99.1
82.9
96.9
N.A.
89.3
83.9
N.A.
33.5
54.5
70.5
68.9
N.A.
35.2
N.A.
34.9
37.9
P-Site Identity:
100
100
100
93.3
N.A.
73.3
73.3
N.A.
0
93.3
20
66.6
N.A.
6.6
N.A.
13.3
6.6
P-Site Similarity:
100
100
100
93.3
N.A.
80
86.6
N.A.
20
93.3
46.6
80
N.A.
13.3
N.A.
33.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
62
24
0
8
0
0
0
0
0
0
0
8
8
0
0
% A
% Cys:
0
62
8
0
0
0
0
8
0
0
0
0
0
0
0
% C
% Asp:
0
0
8
0
0
0
8
0
0
0
0
0
0
0
8
% D
% Glu:
0
0
0
0
8
0
8
0
0
0
8
0
0
0
47
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
8
16
0
0
0
0
0
8
0
8
8
0
0
8
24
% G
% His:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
70
16
24
0
0
0
16
0
0
0
0
0
0
% K
% Leu:
8
0
16
0
0
0
54
8
0
0
0
0
16
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
8
% M
% Asn:
8
0
0
0
0
0
0
0
0
0
24
0
0
54
8
% N
% Pro:
0
0
0
0
0
0
0
0
62
16
0
8
0
8
8
% P
% Gln:
8
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
62
54
70
16
0
0
16
8
8
0
0
0
% R
% Ser:
8
0
0
8
16
8
0
62
16
47
16
70
70
24
0
% S
% Thr:
0
0
0
0
0
8
0
0
0
8
31
8
8
8
0
% T
% Val:
0
0
0
0
0
0
8
0
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
0
0
8
0
8
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _